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Drug Development Update

Note: This document is prepared as a service for the ALS community and is intended as general information. Content used in this report is obtained from informed members of the pharmaceutical industry and the ALS community.

For further information on drug trials, ClinicalTrials.gov provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions.

New Trial for Familial ALS
Announced April, 2005

Now Enrolling

Emory University

Compound or Drug Trial	Status	Company or Center
The Vest	Enrollment Open	American Biosystems, Inc.
AVP-923-Neurodex	Open Label Trial	Avanir Pharmaceuticals
Myotrophin®	Enrollment Open	Cephalon
Minocycline Investigation	Enrollment Open	Eleanor and Lou Gehrig ALS Center at Columbia University
Buspirone Investigation	Currently Enrolling	Multicenter ALS
Creatine	Enrolling patients	The Carolinas Neuromuscular/ALS Center
Ritonavir and hydroxyurea	Now Enrolling	ALS TDF and the Hillblom Foundation
AEOL 10150	Enrolling September 2004	Aeolus Pharmaceuticals
High Dose Coenzyme Q10	Enrollment Open	The Eleanor and Lou Gehrig MDA/ALS Research Center
New Gene Study	Enrollment Open	Massachusetts General Hospital
Ceftriaxone	Pending	Northeast ALS Consortium
National Registry of Veterans with ALS	Enrollment Open	Durham, North Carolina VAMC
Sodium Phenylbutyrate	Enrollment Open	Multicenter